Fall Asleep & Stay Asleep, All Night Long
A lack of quality, restful sleep can affect cognitive health, metabolic health and more. Poor sleep can mean that you have trouble falling asleep, but it can also mean that you wake up in the middle of the night and can’t get back to sleep. Melatonin IR/XR is the perfect sleep support supplement for those who have already tried melatonin but still had trouble getting to sleep or staying asleep.
An estimated 50 to 70 million American adults have difficulty sleeping.1 Melatonin, known as the “sleep hormone,” is made naturally by your body primarily at night and is necessary to keep our day/night rhythm in tune, but those who have trouble sleeping may not be producing enough of it at the right time.2,3,4 Melatonin IR/XR helps you fall asleep and stay asleep all night long. It combines immediate-release and extended-release melatonin for approximately seven hours of healthy sleep support.
MicroActive® Melatonin
Lack of quality, restful sleep can affect cognitive health, metabolic health and more..5,6,7 Each capsule of Melatonin IR/XR contains 1.5 mg of MicroActive® Melatonin, a unique 50/50 blend of immediate- and extended-release melatonin. Taken about 30 minutes before bed, Melatonin IR/XR helps you fall asleep quickly and stay asleep all night long. Just one Melatonin IR/XR capsule provides approximately seven hours of uninterrupted sleep support, so you sleep throughout the night.
Clinical studies on standard immediate-release melatonin Results from an analysis of 15 clinical studies show that standard melatonin helps people fall asleep faster and sleep longer and promotes sleep quality compared with a placebo.8 In one study, subjects took a 0.1 mg, 0.3 mg, or 3 mg melatonin capsule or a placebo 30 minutes before bedtime for three days. All three melatonin doses promoted restful sleep.9 In a recent randomized placebo-controlled trial, subjects who took 0.5 mg fast-release melatonin at night for four consecutive weeks fell asleep faster and experienced healthy, restful sleep compared with a placebo.10
Clinical studies on controlled-release melatonin
A study found that 2 mg of a controlled-release melatonin formulation taken two hours before bed promoted healthy sleep, compared with a placebo, and also shortened the length of time subjects spent awake after initially falling asleep.11 And in another randomized placebo-controlled study, subjects reported improvement in sleep quality after taking 2 mg of an extended-release formulation before bedtime.12
Fall asleep, wake refreshed
For those who sometimes have difficulty sleeping and have tried other melatonin supplements to no avail, now there’s a new formulation from Life Extension. Get the quality, restful and uninterrupted sleep your body needs.
Life Extension supplements begin with meticulous research and a rigorous, science-based approach to developing premium, clinically studied formulations. When we put supplements into our bodies, we should be confident that they’ll provide the nutritional benefits promised. Life Extension’s true passion and dedication has always been driven by the singular goal of optimizing your health so you can live a long, happy life.
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4. ScientificWorldJournal. 2012;2012:640389.
5. Prog Cardiovasc Nurs. 2004;19(2):56-9.
6. Neuropsychiatr Dis Treat. 2007;3(5):553-67.
7. Obes Rev. 2009;10(Suppl 2):37-45.
8. Sleep Med Rev. 2005;9(1):41-50.
9. J Clin Endocrinol Metab. 2001;86(10):4727-30.
10. PLoS Med. 2018;15(6):e1002587.
11. Lancet. 1995;346(8974):541-4.
12. Eur Neuropsychopharmacol. 2003;13(3):137-45.






